1999Synthesis and X-ray crystal structure of trans-dichloro(1-cyano-2.pdfVIP

Polyhedron 18 1999 1863–1868 Synthesis and X-ray crystal structure of trans-dichloro 1-cyano-2,2- dimethylpropane 1-imino-1-hydroxy-2,2-dimethylpropane platinum II a , * a ,1 b b Renzo Cini , Alessandro Cavaglioni , Francesco P. Intini , Francesco P. Fanizzi , b b Concetta Paci?co , Giovanni Natile a ` Dipartimento di Scienze e Tecnologie Chimiche e dei Biosistemi, Universita di Siena, Pian dei Mantellini 44, 53100 Siena, Italy b ` Dipartimento Farmaco-Chimico, Universita di Bari, via E. Orabona 4, 70125 Bari, Italy Received 19 January 1999; accepted 22 March 1999 Abstract Nitrile complexes of platinum easily hydrolyze to amidate, amide, and mixed amide–nitrile complexes. The amide ligands generally adopt the enol tautomeric form and coordinate to platinum through nitrogen. A mixed amide–nitrile complex, trans-[PtCl HN 2 C OH C CH N CC CH ] trans-3 , has shown to be the complex previously formulated as a platinum IV dichlorobisamidate 3 3 3 3 derivative having the two amidate ligands in different tautomeric forms. The structure of trans-3 has been solved by single-crystal diffraction. The complex crystallizes in the Pbcn space group. The crystal structure has strong similarities with that previously reported by some of us for trans-[PtCl HN C OH C CH ] [R. Cini, F.P. Fanizzi, F.P. Intini, C. Paci?co, G. Natile, Inorg. Chim. Acta 264 2 3 3 2 1997 279]. Triplets of complex molecules are stabilized by intra-molecular hydrogen bonds involving N, Cl and O atoms. ? 1999 Elsevier Science Ltd. All rights reserved. Keywords : Platinum; Nitrile; Amide; Intermolecular interaction 1. Introduction 2. Experimental The synthetic and structural chemistry of platinum- 2.1. Materials bound nitriles which are susceptible to nucleophilic attack by alcohols, amines and carbanions to give