外文资料Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats.pdfVIP

J Mol Med DOI 10.1007/s00109-015-1318-7 ORIGINAL ARTICLE Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats Maria Alicia Carrillo-Sepulveda 1,5 Kathryn Spitler 2 Deepesh Pandey3 Dan E. Berkowitz 3 Takayuki Matsumoto4 Received: 12 February 2015 /Revised: 24 June 2015 /Accepted: 26 June 2015 # Springer-Verlag Berlin Heidelberg 2015 Abstract ROS generation and NF- κB activation in VSMCs are at least, Hyperglycemia-induced reactive oxygen species (ROS) pro- i