59项他汀临床研究荟萃分析.pptVIP

Risk Ratio for Coronary Heart Disease Mortality in 59 Randomized Controlled Trials of Cholesterol-Lowering Interventions Statins 0.69 (0.59-0.80) n=13 (16,228/11,279) n-3 fatty acids 0.44 (0.18-1.07) n=3 (1,348/1,349) Fibrates 0.98 (0.78-1.24) n=12 (9,873/11,496) Resins 0.71 (0.51-0.99) n=8 (3,280/3,257 Hormones 1.04 (0.93-1.17) n=8 (4,516/9,039) Niacin acids 0.85 (0.83-1.10) n=2 (1,196/2,932) Diet 0.91 (0.82-1.01) n=16 (48,481/59,042) 1.0 .9 .8 .7 .6 .5 .4 .3 .2 .1 2 Risk Ratio % 95% CI Benefit Harm Arterioscler Thromb Vasc Biol. 1999;19:187-195 Risk Ratio for Overall Mortality in