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《U.S. and Worldwide Monoclonal Antibody Medicine current status and future trends》.pdf
U.S. and Worldwide Monoclonal Antibody Medicine:
Current Status and Future Trends
All sample pages do not display all of a page. It is omitted.
RESEARCH OBJECTIVES
Antibody drugs were a $24 billion business in 2007. Although most pharmaceuticals are
chemically synthesized small molecules, antibodies are large and complex proteins
(immunoglobulins) that act as the human body’s own weapons against infections, diseases
and abnormal cancer cells. Monoclonal antibodies (MAbs) mimic the body’s immune
system with the antibody working as the drug molecule, only MAbs are engineered
artificially outside the body, in the laboratory, rather than by a person’s own immune
system. Furthermore, MAbs are engineered to binding to one particular antigen only.
MAbs are thus important tools for medicine as extremely targeted therapies for treating
patients with severe diseases – especially autoimmune conditions and cancers.
This report analyzes the activities of the leading biopharmaceutical companies with
antibody-based drug products currently on the market or scheduled for introduction soon.
The focus is MAb therapeutics used for treating a disease or condition (as opposed to MAbs
used as a diagnostic or for research). The report details the status of drug makers
antibody pipelines; their alliances, MAs and investments to develop and commercialize
new MAb drugs; and their standing in the battle for market share and bringing a new
best-selling drug to patients. Technological progression in the development of antibody and
protein-based human therapies is overviewed. This report is part of Fuji-Keizai’s ongoing
efforts to track the U.S. and global biopharmaceuticals marketplace.
©Fuji-Keizai USA inc.
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