针灸可否减轻海洛因复吸引起脑结构和神经元的损伤？.docVIP

针灸可否减轻海洛因复吸引起脑结构及神经元的损伤？ 吸食海洛因等阿片类毒品者可造成脑部多个区域损伤，主要集中在中脑被盖脚桥核、中脑腹侧被盖区、伏隔核等脑区。随着复吸次数的增多，使用毒品时间的延长，脑损害逐渐向着不可逆的方向发展，这种损伤可通过形态学改变如神经元的超微结构表现出来。中国安徽中医药大学张荣军所在研究团队进行的一项研究发现，针刺百会、大椎穴后，海洛因复吸模型大鼠中脑腹侧被盖区结构逐渐趋向正常，且此区域脑源性神经营养因子胶质细胞源性神经营养因子脑源性神经营养因子胶质细胞源性神经营养因 针刺海洛因复吸大鼠百会、大椎穴后，其中脑被盖区核膜清楚，核糖体丰富，粗面内质网较丰富，粗面内质网正常或轻度扩张，少数线粒体空泡变性，脑损伤程度明显减轻 Article: Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin relapse, by Rongjun Zhang1, Xinghui Cai1, Xiaoge Song1, Chaoyang Dong2, Xiaorong Hou1, Lei Lv1 (1 Anhui University of Chinese Medicine, Hefei, Anhui Province, China; 2 Anhui Academy of Medical Sciences, Hefei, Anhui Province, China) Zhang RJ, Cai XH, Song XG, Dong CY, Hou XR, Lv L. Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin relapse. Neural Regen Res. 2014;9(3):301-307. 欲获更多资讯：Neural Regen ResAcupuncture normalizes brain structure and damaged neurons following heroin relapse Heroin abuse can damage many brain areas, including the pedunculopontine tegmental nucleus of the midbrain, the ventral tegmental area, and nucleus accumbens. Persistent use of heroin induced irreversible damage to the nervous system. To verify the relationship between acupuncture, neurotrophic factor expression and brain cell structural changes, a research team from Anhui University of Chinese Medicine in China established a rat model of heroin relapse using intramuscular injection of increasing amounts of heroin. During the detoxification period, rat models received acupuncture at Baihui (DU20) and Dazhui (DU14). Rongjun Zhang and co-workers from this team found that the structure of the ventral tegmental area in heroin relapse rats gradually became normalized after acupuncture treatment, and the expression of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor also increased in the ventral tegmental area following acupuncture. These results, published in the Neural Regeneration Research