Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease a randomized controlled clinical study》.pdf

OnlineSubmissions: JTraditChinMed2013December15;33(6):733-742 info@ ISSN0255-2922 ©2013JTCM.Allrightsreserved. CLINICALSTUDYTOPIC Reduninginjectionforfever,rash,andulcersinchildrenwithmild hand,foot,andmouthdisease:arandomizedcontrolledclinical study GuoliangZhang,JieZhao,LiyunHe,ShiyanYan,ZiqiangZhuo,HaojieZheng,YongpingMu,ShuangjieLi,Xi Zhang,JihanHuang,XiuhuiLi,JianpingLiu,HeheWan,ChaoyuWei,WeiXiao aa Guoliang Zhang, Department of Infectious Disease, the Abstract FirstAffiliatedHospitalofAnhuiUniversityofChineseMedi- cine,Hefei230038,China OBJECTIVE:ToassesstheefficacyandsafetyofRe- JieZhao,HeheWan,ChaoyuWei,GraduateFaculty,Anhui duninginjectionforfever,rash,andulcersinchil- UniversityofChineseMedicine,Hefei230038,China dren with mild hand, foot, and mouth disease LiyunHe,ShiyanYan, ChineseMedicalClinicalBasicRe- (HFMD). searchInstitute,ChinaAcademyofChineseMedicalScienc- es,Beijing100700,China METHODS: A stratified-block randomized, dou- Ziqiang Zhuo, Department of Infectious Disease, Quan- ble-blind,parallel-controlled,andmulticenterclini- zhouChildrensHospital,Quanzhou362017,China caltrialwasconductedwith360patientsinfive HaojieZheng,DepartmentofCombineTraditionalChinese hospitalsacrossChina:QuanzhouChildrensHospi- andWesternMedicine,Shijiazhuang050021,China tal,ShijiazhuangNo.5Hospital,ShanghaiPublic YongpingMu, DepartmentofCombineTraditionalChinese HealthCentre,HunanProvincialChildrensHospi- and Western Medicine, Shanghai Public Health