食物过敏的诊断方法.pdfVIP

312 ·综述· 食物过敏的诊断方法 张咿讳 王学民王婷婷孙丽囡 【摘要】食物过敏是指免疫介导的食物不良反应，是婴幼儿常见的过敏性疾病，患儿家长对食物过 敏的错误认识及诊断的不明确，导致一系列的喂养和健康问题。IgE介导的食物过敏机制是多因素的，主 要受遗传体质和环境的相互作用；非IgE介导的食物过敏的机制尚不清楚。目前认为，其主要由T细胞介 导，可引起亚急性或慢性胃肠道或皮肤反应。因此，了解食物过敏诊断相关的临床检查方法，结合临床病 史、饮食排除试验、食物激发试验等方法正确诊断食物过敏，对减少食物过敏反应的发生以及指导正确的 规避饮食和相应的免疫治疗具有重要意义。 【关键词】食物过敏；诊断；方法；免疫；健康教育 methodsforfood Unan．‘skinand Diagnostic aHergyZhangYi订，WangXuemin，WangTingfing,Sun CosmeticReseareh SkinDisease 200443，∞ina Department．ShanghaiHospital，Shanghai Xuemin，Emaih CorrespondinganthorWang dermxmwang@126．tom animmune—mediatedadversereactionto acommon 【Abstract】Foodallergy，as food，is allergicproblem ininfants．The offood inchildren’S andindefinite haveleadedtoa misunderstandingallergy parents diagnosis seriesof andhealth mechanismof food iSmultifactorial．andiS feeding problems．The IgE—mediatedallergy themechanismof associatedwiththeinteractionbetween andenvironment，while mainly geneticpredisposition itis bemediated T cancause mediatedfood iSunclear．andconsideredto cells．and non—IgE allergy mainlyby orchronic orskinreactions．Therefore．itiSof to subaeute gastrointestinal greatsignificanceexpandknowledge 013clinical methodsforfood to food medical diagnostic allergy，andcorrectlydiagnoseallergybycombining diettrialsandoralfood resultsfor theoccurrenceoffood history，elimination challenge reducing allergy， eliminationdietand guiding correspondingimmunotherapy． 【Keywords】Food education hypersens