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Sedimentation studies of the size and shape of DNA》.pdf
J. Mol. Biol. (1965) 11, 373-390
Sedimentation Studies of the Size and Shape of DNA
F. WILLIAM STUDIERt
Department of Biochemistry, Stanford University School of Medicine
Palo Alto, CaliJ., U.S.A.
(Received 15 October 1964, and in revisedform 9 November 1964)
Analytical zone sedimentation (Vinograd, Bruner, Kent Weigle, 1963) is
shown to be a sensitive and reliable method for detecting differences in conforma-
tion and for determi
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