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Single-Event Analysis of the Packaging of Bacteriophage T7 DNA Concatemers in Vitro》.pdf
Biophysical Journal Volume 77 September 1999 1627–1637 1627
Single-Event Analysis of the Packaging of Bacteriophage T7 DNA
Concatemers in Vitro
Mao Sun, Donna Louie, and Philip Serwer
Department of Biochemistry, The University of Texas Health Science Center, San Antonio, Texas 78284-7760 USA
ABSTRACT Bacteriophage T7 packages its double-stranded DNA genome in a preformed protein capsid (procapsid). The
DNA substrate for packaging is a head-to-tail multimer (concatemer) of the mature 40-kilobase p
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