Stem Cells and the Niche A Dynamic Duo》.pdfVIP

Cell Stem Cell Review Stem Cells and the Niche: A Dynamic Duo Justin Voog1,2 and D. Leanne Jones1,3,* 1Laboratory of Genetics, The Salk Institute for Biological Studies 2Department of Biomedical Sciences 3Division of Biological Sciences University of California, San Diego, La Jolla, CA 92037, USA *Correspondence: ljones@salk.edu DOI 10.1016/j.stem.2010.01.011 Stem cell niches are dynamic microenvironments that balance stem cell activity to maintain tissue homeo- stasis and repair throughout the lifetime of an organism. The development of strategies to monitor and per- turb niche c