ExerciseAdenosineStressTestReport-EndocrineSociety.doc

The Endocrine Society Oral History Collection The Clark Sawin Library Jean D. Wilson, Md Interview conducted by Michael Chappelle June 19, 2010 Copyright ? 2010 by The Endocrine Society All uses of this manuscript are covered by a legal agreement between The Trustees of The Endocrine Society and Jean Wilson, dated June 19, 2010. The manuscript is thereby made available for research purposes. All literary rights in the manuscript, including the right to publish, are reserved to The Clark Sawin Library. No part of the manuscript may be quoted for publication without the written permission of the Director of Clark Sawin Library. Requests for permission to quote for publication should be addressed to The Endocrine Society Office, The Clark Sawin Library, Chevy Chase, Maryland, 20815, and should include identification of the specific passages to be quoted, anticipated use of the passages, and identification of the user. It is recommended that this oral history be cited as follows: Jean D. Wilson, MD, an oral history conducted in 2010 by Michael Chappelle, The Endocrine Society, The Clark Sawin Library, Chevy Chase, Maryland, 2010.  INTRODUCTION Jean D. Wilson, MD, holder of the Charles Cameron Sprague Distinguished Chair in Biomedical Science, University of Texas Southwestern Medical Center has devoted most of his 55-year career in the medical sciences to understanding sexual differentiation. His studies of androgens, together with Elwood Jensens studies of estrogens, demonstrated that steroid hormones localize to the nucleus and prefigured the discovery of nuclear hormone receptors. Dr. Wilson’s research also directed attention to the role of dihydrotestosterone in a common disorder, benign prostatic hyperplasia, which led to the first successful medical therapy of this condition. In addition to these extraordinary scientific achievements, his career as physician-scientist has been characterized by outstanding leadership in professional societies and exceptio