左冠状动脉主干及其分支间的夹角与左冠状动脉斑块形成的相关性分析.docVIP

左冠状动脉主干及其分支间的夹角与左冠状动脉斑块形成的相关性分析 吴渝千，陈 婷，郭大静，方 正，刘 佳 （400010 重庆，重庆医科大学附属第二医院放射科） [摘要] 目的 利用冠脉CT血管成像（CT angiography, CTA）探讨左冠脉主干（left main coronary artery, LM）、左前降支（left anterior descending branch, LAD）、左回旋支（left circumflex branch, LCX）三者间的夹角与局部斑块形成和分布特征之间的相关性。方法 对127例行冠脉CTA检查患者进行回顾性研究，分为正常组44例和左冠脉病变组83例，病变组进一步分为LM组18例，近段组57例，中远段组8例。在重建图像上测量LM、LAD、LCX°时，左冠脉斑块形成机率将会增加。结论 LM、LAD、LCX三者间的夹角与左冠脉斑块的形成和分布具有相关性。 [关键词] 冠脉；CT血管成像；角度；斑块 [中图法分类号] R541.4；R814.42 [文献标志码] A The correlation between intersection angles of left main coronary artery and its branches and formation of atherosclerotic plaques Wu Yuqian, Chen Ting, Guo Dajing, Fang Zheng, Liu Jia (Department of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China) [Abstract] Objective To investigate the relationship between intersection angles among left main coronary artery (LM), left anterior descending branch (LAD) and left circumflex branch (LCX) and formation and distribution of atherosclerotic plaques in the left coronary artery by employing 320-row CT angiography (CTA). Methods 127 patients underwent CTA examinations were retrospectively reviewed, including the normal group (n=44) and left coronary artery lesion group (n=83) which were divided into three sub-groups: the LM group (n=18), the proximal group (n=57) and the middle and distal group (n=8). The intersection angles among LM, LAD and LCX should be measured on the reconstructed images, and then the relationships between intersection angles among LM, LAD and LCX and formation and distribution of atherosclerotic plaques were analyzed. Results The angles of LM-LAD and LM-LCX negatively correlated with the angle of LAD-LCX (the bifurcation angle) in 127 patients, and the correlation coefficients were ﹣0.356 and﹣0.662, respectively (P＜0.05). There was significant difference in the bifurcation angle between the proximal group (90.9±20.0) and the normal group (72.7±16.7) (P＜0.05). Comp