氟伐他汀逆转斑块应用研究.pptVIP

* 通过对JUPITER的结果再分析我们看到：hs-CRP达到值的不同以及降低幅度的不同确实影响了患者的心脏预后。 * JUPITER结果证实，hs－CRP的下降是他汀的独立作用，与LDL-C的下降无关 Rosuvastatin reduced the median LDL cholesterol by50% (p0·0001) and the median hsCRP by 37%compared with placebo (p0·0001). However, the magnitude of correlation between achieved LDL cholesterol and achieved hsCRP in participants given rosuvastatin was small (r=0·10), so that less than 2% of the variance in achieved hsCRP was explained by the variance in achieved LDL cholesterol. The correlations between achieved hsCRP and achieved Apolipoprotein B (r=0·10), between achieved hsCRP and the ach