亚砜及亚磺酰胺类配体催化不对称反应的新进展有机化学.pdfVIP

DOI: 10.6023/cjoc201308029 综述与进展 有机化学 Chinese Journal of Organic Chemistry REVIEW 亚砜及亚磺酰胺类配体催化不对称反应的新进展 薛 峰*,a,b 李长恭a 陈 洁a 万伯顺*,b (a 河南科技学院化学化工学院 河南省新乡市功能有机分子重点实验室 新乡 453002) (b 中国科学院大连化学物理研究所 大连 116023) 摘要 亚砜及亚磺酰胺类化合物作为手性配体催化不对称反应是目前研究最为活跃的领域之一, 苯环骨架以及链状骨 架的亚砜及亚磺酰胺类手性配体相继成功地用于不对称反应中. 主要综述了近年来含亚砜及亚磺酰胺类的手性配体催 化不对称反应的研究进展. 关键词 亚砜及亚磺酰胺类化合物; 手性配体; 不对称催化 Recent Progress of Sulfoxide and N-Sulfinyl Ligands in Asymmetric Catalysis Xue, Feng*,a,b Li, Changgonga Chen, Jiea Wan, Boshun*,b a ( Key Laboratory of Functional Organic Molecules of Xinxiang City Henan Province, Chemistry College of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453002) b ( Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023) Abstract Chiral ligands based on sulfoxide and N-sulfinyl compounds in asymmetric reaction have recently become an in- creasingly active research area, in which benzene-backboned or linear sulfoxides and their derivatives as ligands have been successively applied in asymmetric reaction. In this review, the recent progress of the chiral ligands containing sulfoxide and N-sulfinyl moieties in the asymmetric reactions is mainly reviewed. Keywords sulfoxide and N-sulfinyl compounds; chiral ligands; asymmetric catalysis 在手性金属催化中, 其核心之一就是设计与合成优 化反应中. 本文主要综述最近发展的双亚砜、膦亚砜、 良的手性配体. 多年来, 人们合成出众多结构各异的手 烯亚砜及烯亚磺酰胺类