A Cultural Algorithm for the Representation of Mitochondrial Population.pdfVIP

Hindawi Publishing Corporation Advances in Artificial Intelligence Volume 2012, Article ID 457351, 7 pages doi:10.1155/2012/457351 Research Article A Cultural Algorithm for the Representation of Mitochondrial Population Athanasios Alexiou and Panayiotis Vlamos Department of Informatics, Ionian University, Plateia Tsirigoti 7, 49100 Corfu, Greece Correspondence should be addressed to Athanasios Alexiou, alexiou@ionio.gr Received 31 May 2012; Accepted 14 August 2012 Academic Editor: Catalina Cocianu Copyright © 2012 A. Alexiou and P. Vlamos. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We propose a novel Cultural Algorithm for the representation of mitochondrial population in mammalian cells as an autonomous culture. While mitochondrial dysfunctions are highly associated with neurodegenerative diseases and related disorders, an alternative theoretical framework is described for the representation of mitochondrial dynamics. A new perspective of bioinspired algorithm is produced, combining the particle-based Brownian dynamics simulation and the combinatorial representation of mitochondrial population in the lattice, involving the optimization problem of ATP production in mammalian cells. 1. Introduction in terms of the transmission of behaviors or traits between individuals in a population and a macroevolutionary per- Considering the latest researches, disruptions in the regu- spective in terms of the formation of generalized beliefs based lation of mitochondrial