Epidemiology, Diagnosis, and Treatment of HIV-Associated Non-Hodgkin Lymphoma in Resource-Limited Settings.pdfVIP

Hindawi Publishing Corporation Advances in Hematology Volume 2012, Article ID 932658, 7 pages doi:10.1155/2012/932658 Review Article Epidemiology, Diagnosis, and Treatment of HIV-Associated Non-Hodgkin Lymphoma in Resource-Limited Settings Matthew Ulrickson,1 Oliver W. Press,2 and Corey Casper3 1 Department of Medicine, University of Washington/Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 2 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 3 Vaccine and Infectious Disease, Public Health Sciences, and Clinical Research Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA Correspondence should be addressed to Matthew Ulrickson, mulrick@ Received 1 December 2011; Accepted 23 January 2012 Academic Editor: Lisa K. Hicks Copyright © 2012 Matthew Ulrickson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Lymphoma was a common complication of HIV infection in the pre-antiretroviral era, and the incidence of HIV-associated lymphoma has dropped dramatically since the introduction of combination antiretroviral therapy (cART) in resource-rich regions. Conversely, lymphoma is an increasingly common complication of HIV infection in resource-limited settings where the prevalence of HIV infection is high. Relatively little is known, however, about the true incidence and optimal treatment regimens for HIV- associated lymphoma in resource-poor regions. We review the epidemiology, diagnosis, and treatment of HIV-associated non- Hodgkin lymphoma in developing nations and highlight areas for further research that may benefit car