Making chemistry selectable by linking it toinfectivity.PDFVIP

Proc. Natl. Acad. Sci. USA Vol. 94, pp. 11777–11782, October 1997 Chemistry Making chemistry selectable by linking it to infectivity CHANGSHOU GAO, CHAO-HSIUNG LIN, CHIH-HUNG L. LO, SHENLAN MAO, PETER WIRSCHING, RICHARD A. LERNER *, AND KIM D. JANDA† Departments of Chemistry and Molecular Biology, The Scripps Research Institute and The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037 Contributed by Richard A. Lerner, August 21, 1997 ABSTRACT The link between recognition and replication the implementation of this ap