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Mitotic Spindle Form and Function.PDF
YEASTBOOK
CELL STRUCTURE TRAFFICKING
Mitotic Spindle Form and Function
Mark Winey* and Kerry Bloom†,1
*Molecular Cell and Developmental Biology, University of Colorado, Boulder, Colorado 80309 and †Department of Biology, University of North
Carolina, Chapel Hill, North Carolina 27599-3280
ABSTRACT The Saccharomyces cerevisiae mitotic spindle in budding yeast is exemplified by its simplicity and elegance. Microtubules are
nucleated from a crystalline array of proteins organized in the nuclear envelope, known as the spindle pole body in yeast (analogous to the
centrosome in larger euk
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