Mechanism of Chemical Activation of Nrf2.PDFVIP

Mechanism of Chemical Activation of Nrf2 1,2 1 1 Yun Li , Joseph D. Paonessa , Yuesheng Zhang * 1 Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America, 2 Department of Urology, Roswell Park Cancer Institute, Buffalo, New York, United States of America Abstract NF-E2 related factor-2 (Nrf2) promotes the transcription of many cytoprotective genes and is a major drug target for prevention of cancer and other