原创力文档Leptin action via LepR-b Tyr1077 contributes to the control of energy balance and female reproduction.PDFVIP
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Leptin action via LepR-b Tyr1077 contributes to the control of energy balance and female reproduction.PDF
Original article
Leptin action via LepR-b Tyr1077 contributes to the
control of energy balance and female reproduction
Christa M. Patterson a,1, Eneida C. Villanueva a,b,1 , Megan Greenwald-Yarnell a,c , Michael Rajala a,d,
Ian E. Gonzalez a , Natinder Saini e, Justin Jones a , Martin G. Myers Jr.a,b,c,*
ABSTRACT
Leptin action in the brain signals the repletion of adipose energy stores, suppressing feeding and permitting energy expenditure on a variety of
processes, including reproduction. Leptin binding to its receptor (LepR-b) promotes the tyrosine phosphorylation of three sites on
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