Modeling the Establishment of PAR Protein Polarity in the One-Cell C. elegans Embryo.PDFVIP

4512 Biophysical Journal Volume 95 November 2008 4512–4522 Modeling the Establishment of PAR Protein Polarity in the One-Cell C. elegans Embryo Filipe Tostevin* and Martin Howardy *Department of Mathematics, Imperial College London, London, United Kingdom; and yDepartment of Computational and Systems Biology, John Innes Centre, Norwich, United Kingdom ABSTRACT At the one-cell stage, the C. elegans embryo becomes polarized along the anterior-posterior axis. The PAR proteins form complementary a