原创力文档Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication.PDFVIP
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Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication.PDF
Tynell et al. Virology Journal 2014, 11:128
/content/11/1/128
RESEARCH Open Access
Mutations within the conserved NS1 nuclear
export signal lead to inhibition of influenza A
virus replication
Janne Tynell 1*, Krister Melén1 and Ilkka Julkunen1,2
Abstract
Background: The influenza A virus NS1 protein is a virulence factor and an antagonist of host cell innate immune
responses. During virus infection NS1 protein has several functions both in the nucleus and in the cy
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