Nucleocytoplasmic Shuttling of Polypyrimidine Tract-binding Protein Is Uncoupled from RNA Export.PDFVIP

Molecular Biology of the Cell Vol. 12, 3808–3820, December 2001 Nucleocytoplasmic Shuttling of Polypyrimidine Tract-binding Protein Is Uncoupled from RNA Export Rajesh V. Kamath, Daniel J. Leary, and Sui Huang* Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611 Submitted July 6, 2001; Revised August 21, 2001; Accepted September 5, 2001 Monitoring Editor: Marvin P. Wickens Polypyrimidine tract binding protein, PTB/hnRNP I, is involved in pre-mRNA processing in the nucleus and RNA localization and translation in th