几种柏科植物挥发物质和抗肿瘤活性初步研究_蒋继宏.pdfVIP

33 2 Vol33 No2 2 0 0 6 6 Jour of Fujian Forestry Sci and Tech Jun, 2 0 0 6 1 1,2 1 1 1 1 2 蒋继宏, 李晓储 , 高甜惠, 何冬宁 , 陈凤美, 张艳平 , 黄利斌 ( 1徐州师范大学江苏省药 植物生物技术重点实验室, 江苏 徐州221000; 2江苏省林业科学研究院, 江苏 南京211153) : Alamar blue 5 , , 5 NCI-H460 3693% 784% 7377% 8122% 5653% , NCI-H460 - 6 , 527 : ; ; ; : TQ4607 2; R7345 : A : 1002- 7351(2006) 02- 0052- 06 Volatile Constituents from theCupressaceae Plants and Their Antitumor Activities 1 1,2 1 1 1 1 2 JIANGJ-i hong , LI Xiao-chu , GA Tian-hui , HE Dong-ning ,CHEN Feng-mei ,ZHANGYan-ping , HUANGLi-bing ( 1Key Laboratoryf or Biotechnology on Medicinal Plants of JiangsuProvince, XuzhouNormal University, Xuzhou 221000, hina; 2. Jiangsu Academy of Forestry Nanj ing 211153) Abstract:The ant itumor activities of volatile constituents from the Cupressaceae plants against human lung cancer cell line NCI- H460 w ere determined by alamar blue assay. The results showed that the inhibiting rates of volatile constituents from Jun ip er us f or mosana, S abina ch inensis , S a bina ch inensis cv. Kaizuca, Chamaecyp ar is obt use and Chamaecyp ar is p isif er a Endt var. sq uar r os against human lung cancer cell line NCI-H460 were 36. 93% 784% 7377% 8122% and 56. 53% , respect ively. And the volatile constituents from Chamaecyp ar is obtuse against the lung cancer line w as strongest. These volatile constituents from the five Cupressaceae plants were analyzed by capillary GC-MS method. The kinds of the volat ile constituents from Jun ip er usf or mosana, S a bina ch inensis, S abina chinensis cv. Kaizuca, Chamaecyp ar is obtuse and Chamaecyp ar is p isif er a Endt var. squ