fMRI-2004-Smith提取情绪背景的fMRI关联.pdfVIP

/locate/ynimg NeuroImage 22 (2004) 868– 878 fMRI correlates of the episodic retrieval of emotional contexts A.P.R. Smith, a,b,* R.N.A. Henson, a,b R.J. Dolan, a and M.D. Ruggb,c,1 a Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK b Institute of Cognitive Neuroscience, University College London, London, UK c Department of Psychology, University College London, London, UK Received 30 October 2003; revised 7 January 2004; accepted 30 January 2004 Functional neuroimaging studies reveal differences in neural correlates emotional and neutral pictures as recognition cues leads to diffi- of the retrieval of emotional and nonemotional memories. In the culties in interpreting whether the observed effects reflected present experiment, encoding of emotionally neutral pictures in exclusively memory-related processes or included activity resulting association with positively, neutrally or negatively valenced back- from on-line processing of emotional information (see also Mar- ground contexts led to differential modulation of neural activity elicited atos and Rugg, 2001; Smith et al., in press). in a subsequent recognition memory test for these pictures. Recognition A number of recent studies, using event-related designs, have of stimuli previously studied in emotional compared to neutral contexts investigated emotional retrieval with designs enabling contrasts of elicited enhanced activity in structures previously implicated in episodic memory, including the parahippocampal cortex, hippocampus