AD诊断标准演变要点.pptVIP

影像学及生物标记 MRI： 内颞叶萎缩的发生率 PET：脑组织糖代谢显像、特异性老年斑显像等 老年斑显像剂：1-{6-[(2-18F-氟乙基)-甲氨基]-2-萘基}-亚乙基丙二氰(18F-FDDNP)和匹兹堡复合物B ( Pittsburgh Compound-B, PIB) CSF：Aβ42、t-tau、p-tau等改变反映AD的分子病理特征 AD MCI Nor 71-96% 59-78% 29% * * * * * Gary--I would change the display range so they can more easily see the deficits in ther normal memory APOE-4 patient. They only get a quick look need to easily see this. A 14 6 % change is a big one should seen easily in the was it is displayed. Company Logo AD诊断标准演变 王磊 一、背景 Alzheimer‘s disease,AD 所谓的老年性痴呆症，为痴呆最常见的病因和最常见的老年期痴呆。 据中国阿尔茨海默病协会2011年的公布调查结果显示，全球有约3650