小儿GERD诊断标准探讨附12年4158例食管pH值监测结果 ….pptVIP

Esophageal histological features of GERD Basal zone hyperplasia (20% of total thickness) Elongation of papillae (50% of total thickness) Infiltration with neutrophils or eosinophils (15/high power field) The presence of dilated intercellular spaces Growing of blood vessels in papilla Histological changes are neither sensitive nor specific for reflux disease in NERD cases and should not be used alone to diagnose or exclude GERD Poddar U. Indian Pediatr 2013 Tobey NA, et al. Gastroenterology 1996 Boccia G, et al. Am J Gastroenterol 2007 Vandenplas Y, et al. J Pediatr Gastroenterol Nutr 2009 Bar