Predictive data mining in clinical strongmedicinestrong Current issues.pdfVIP

i n t e r n a t i o n a l j o u r n a l o f m e d i c a l i n f o r m a t i c s 7 7 ( 2 0 0 8 ) 81–97 j o u rn al h omepage: www.i /jou rna l s / i jm i Review Predictive data mining in clinical medicine: Current issues and guidelines Riccardo Bellazzi a,∗, Blaz Zupan b,c a ` Dipartimento di Informatica e Sistemistica, Universita di Pavia, via Ferrata 1, 27100 Pavia, Italy b Faculty of Computer Science, University of Ljubljana, Slovenia c Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX, United States a r t i c l e i n f o a b s t r a c t Article history: Background: The widespread availability of new computational methods and tools for data Received 27 October 2006 analysis and predictive modeling requires medical informatics researchers and practitioners Accepted 17 November 2006 to systematically select the most appropriate strategy to cope with clinical prediction prob- lems. In particular, the collection of methods known as ‘data mining’ offers methodological and technical solutions to deal with the analysis of medical data and construction of predic- Keywords: tion models. A large variety of these methods requires general and simple guidelines that Data mining may help practitioners in the appropriate selection of data mining tools, construction and Predictive models validation of predictive models, along with the dissemination of predictive models within Clinical medicine clinical environments.