Postacquisition Detection of Tumor Motion in the Lung and.pdfVIP

Postacquisition Detection of Tumor Motion in the Lung and Upper Abdomen Using List-Mode PET Data: A Feasibility Study ´ ´ ´ ´ Ralph A. Bundschuh, Axel Martınez-Moeller, Markus Essler, Marıa-Jose Martınez, Stephan G. Nekolla, Sibylle I. Ziegler, and Markus Schwaiger Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany ¨ ¨ One of the main degrading factors in the quality of oncologic PET Because PET can deliver unique information on the images of the thorax and upper abdomen is respiratory motion of metabolism of cancer lesions, interest in using it for tumor tumors. One method to reduce this effect is the acquisition of staging, radiation treatment planning, and therapy control PET data in gated mode. A second method is the correction of studies for motion. Motion registration is essential in both cases. has increased in recent years. Because the acquisition takes We report a method using list-mode data to detect the cranio- several minutes per bed position, the quantitative accuracy caudal (z) movement of thoracic and abdominal lesions without of the PET images is strongly reduced by movement of the using any external gating device. The aim of this study was to patient. Especially in the region of the lung and upper show the feasibility of applying this method to patient data. abdominal organs, where tumors can move up to 2 cm be- Methods: For 10 patients with lesions in the lung or upper ab- cause of respiration (1),