imaging without lenses achievements and remaining challenges.pdfVIP

perspective imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy Alon Greenbaum1,2, Wei Luo1,2, Ting-Wei Su1,2, Zoltán Göröcs1,2, Liang Xue1–3, Serhan O Isikman1,2, Ahmet F Coskun1,2, Onur Mudanyali1,2 Aydogan Ozcan1,2,4,5 We discuss unique features of lens-free we can categorize bright-field lens-free microscopes . computational imaging tools and report some into two main streams: (i) contact-mode shadow d e of their emerging results for wide-field on-chip imaging–based microscopes18–2 1 and (ii) diffraction- v r e microscopy, such as the achievement of a numerical based lens-free microscopes 1–17. The first group of s e r aperture (na) of ~0.8–0.9 across a field of view lens-free microscopes is designed to minimize the s t 2 h (Fov) of more than 20 mm or an na of ~0.1 across distance (ideally less than 1 µm) between the sample g i 2 r a Fov of ~18 cm , which corresponds to an image l and the active region of the sensor array (or an aper- l A with more than 1.5 gigapixels. We also discuss the