a novel molluscan fos gene with immune defense function identified in the hong kong oyster, crassostrea hongkongensis：一种新的软体动物fos基因与免疫防御功能在香港牡蛎，近江牡蛎.pdfVIP

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a novel molluscan fos gene with immune defense function identified in the hong kong oyster, crassostrea hongkongensis：一种新的软体动物fos基因与免疫防御功能在香港牡蛎，近江牡蛎.pdf

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a novel molluscan fos gene with immune defense function identified in the hong kong oyster, crassostrea hongkongensis：一种新的软体动物fos基因与免疫防御功能在香港牡蛎，近江牡蛎

Developmental and Comparative Immunology 51 (2015) 194–201 Contents lists available at ScienceDirect Developmental and Comparative Immunology journal homepage: /locate/dci A novel molluscan Fos gene with immune defense function identiﬁed in the Hong Kong oyster, Crassostrea hongkongensis Fufa Qu a,b, Zhiming Xiang a, Fuxuan Wang a,b, Yang Zhang a, Ying Tong a, Jun Li a, Yuehuan Zhang a, Ziniu Yu a,* a Key Laboratory of Tropical Marine Bio-resources and Ecology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China b University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, China A R T I C L E I N F O A B S T R A C T Article history: The transcription factor Fos is a member of one of the best-studied AP-1 sub-families and has been im- Received 17 February 2015 plicated in a wide variety of biological processes, including the regulation of apoptosis, immune responses Revised 27 March 2015 and cytokine production. In this report, a novel mollusk Fos (referred to as ChFos) gene was cloned and Accepted 28 March 2015 characterized from the Hong Kong oyster, Crassostrea hongkongensis. The deduced ChFos protein se- Available online 1 April 2015 quence comprised 333 amino acids and shared signiﬁcant homology with invertebrate homologs. Phylogenetic analysis revealed that ChFos clusters with Fos from Crassostrea gigas and Crassostrea ariakensis. Keywords: