a score for predicting paroxysmal atrial fibrillation in acute stroke patients ipab score：对急性脑卒中患者阵发性心房颤动的ipab评分评分预测.pdfVIP

A Score for Predicting Paroxysmal Atrial Fibrillation in Acute Stroke Patients: iPAB Score * Kotaro Yoshioka, MD, † Kosuke Watanabe, MD,† Satoshi Zeniya, MD,‡ Yoko Ito, MD,‡ Masaki Hizume, MD, PhD,† Toshiro Kanazawa, MD, PhD,† Makoto Tomita, PhD,x Satoru Ishibashi, MD, PhD,* Hirotomo Miake, MD, PhD,‡ Hiroaki Tanaka, MD, PhD,† Takanori Yokota, MD, PhD,* and Hidehiro Mizusawa, MD, PhD* Background: Detection of paroxysmal atrial fibrillation (PAF) after a stroke is chal- lenging. The purpose of this study was to develop a clinical score to predict PAF in a cohort of acute ischemic stroke patients prospectively and to validate it in an in- dependent cohort. Methods: Consecutive acute ischemic stroke patients without per- manent atrial fibrillation were enrolled in a derivation sample (n 5 294) or a validation sample (n 5 155). We developed a score for predicting PAF by indepen- dent risk factors derived from a logistic regression analysis of the derivation cohort and validated the score in the external cohort. Results: Multivariate analysis in the derivation cohort identified 3 variables independently associated with PAF. We calculated a score from these variables (history of arrhythmia or antiarrhythmic agent use [yes, 3 points], left atrial dilation [$40 mm, 1 point], brain natriuretic pep- tide [BNP, $50 pg/mL, 1 point; $90 pg/mL, 2 points; $150 pg/ml, 3 points], total score, 0-7). The iPAB score (identifie