82例原发性胃漫大b细胞淋巴瘤的临床分析.pdfVIP

摘要 摘要 diffuse 目的：探讨原发性胃弥漫大B细胞淋巴瘤(primarygastric large B-cell 治疗方式及预后因素。 素生存预后分析，多因素分析采用Cox回归模型。其中采用手术加化疗44例， 手术加化放疗5例，化放疗8例，单纯手术8例，单纯化疗15例，未治疗2例。 生存率均分别为64．2％和59．3％。手术+化疗或放化疗组与化疗或放化疗联合组 发现国际预后指数(internationalprognosis 果表明初诊时血清LDH水平与临床分期是影响本组患者预后的独立因素。 生存和指导治疗有重要作用，其中初诊时血清LDH水平与临床分期是本组患者 的独立预后因素。术后化疗或术后放化疗组的疗效与化疗或放化疗组相比基本 相同。 关键词：胃肿瘤；弥漫大B细胞淋巴瘤；临床特征；细胞来源；预后 Abstract ABSTRACT Objective： To theclinical characteristics，cellprognosisof(primary investigate origin，and diffuseB—cell effectivetreatment explore gastric large lymphoma(PG-DLBCL)，and and rattersof forPG—DLBCL． patternsprognosticpatients Method： Clinicaldataof82PG—DLBCL andtreatedinTheFirst patients，diagnosed Affiliated of from2001 to2009，wereretrospectively NanchangUniversity Hospital ratewas factorswere analyzed byKaplan-Meiermethod，prognosis analyzed．Survival Cox of82 test，and model_multivariate patients bylog—rank ananlysis．Forty-four received received chemotherapy,5surgeryplus surgeryplus received received 5received alone，1 chemotherapy chemoradiotherapy,8surgery 2wereuntreated． alone，and Results： Themedianofthe82 was