舒冠通络方对不稳定型心绞痛气滞络瘀证患者血清VEGF与bFGF的干预的分析.pdfVIP

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舒冠通络方对不稳定型心绞痛气滞络瘀证患者血清VEGF与bFGF的干预的分析.pdf

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善冠脉血供，从而达到较好的治疗效果，为临床治疗不稳定型心绞痛气滞络瘀证患者提供参考。关键词舒冠通络方；不稳定型心绞痛；气滞络瘀；血管内皮生长因子；碱性成纤维细胞生长因子；临床研究 The Clinical Study of VFGF and bFGF on the effect of ShuGuanTongLuo formula in Treating the Qi stagnancy and Collaterals stasis of Unstable Angina Pectoris(UAP) Speciality： Internal medicine of TCM Author ： Zhang Jin Tutor： Pro. Zhang Yunhui ABSTRACT Background Coronary heart disease is a common one of cardiovascular disease， coronary atherosclerosis make the blood vessels of the luminal stenosis ，obstruction or spasm myocardial ischemia，lack of oxygen and cause heart attacks. At present，drug therapy ，interventional therapy and surgical treatment is generally recognized international three treatment way. Intervention and surgical treatment has certain limitation ，can only make narrow again the part and cannot effect a radical cure coronary heart disease. The 20th century ，some scholars proposed by increasing the coronary artery branch and establish collateral circulation and restore the myocardial blood for blood vessels of the new treatment new ideas. In recent years ，Chinese traditional medicine the mechanism of action of angiogenesis to become the research focus. Objective This study was to observe ShuGuanTongLuo formula to unstable angina patients angiogenic factors of vascular endothelial growth factor (vascular endothelial growth factor; VEGF) and basic fibroblast growth factor (basic fibroblast growth factor; bFGF) role of intervention ，and discussed its， mechanism. Methods 60 patients with unstable angina patients were randomly divided the into treatment group(30 cases) and the control group(30 cases) ，10 cases of healthy check-up patients will be set to blank control group ， the treatment group and the contro