健脾补肾方联合p方案治疗术后非小细胞肺癌的临床研究.pdfVIP

健脾补肾方联合p方案治疗术后非小细胞肺癌的临床研究.pdf

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健脾补肾方联合p方案治疗术后非小细胞肺癌的临床研究

Clinical Study on Postoperative Non-small Cell Lung Cancer Treated By “Jian pi bu shen fang”Combined With Chemotherapy Speciality: Internal Medicine of TCM Author: Zhou Qing Tutor: Professor Qi Yuanfu Abstract Objective:Deficiency of both vital energy and yin is one of the basic pathogenesis of lung cancer.Supplementing qi and nourishing yin is one of the most important principles of treatment. Based on it ,we choose“Jian pi bu shen fang”combined with chemotherapy (DP regimen) to study the curative effect of Chinese medicines and chemotherapy on postoperative non-small cell lung cancer.Methods:40 postoperative cases with non-small cell lung cancer were randomly divided into two groups.20 patients in the treated group were administered with “Jian pi bu shen fang” and chemotherapy (DP regimen),20 in the control group with chemotherapy alone.Objective effects and the changes of subjective symptoms were studied during both periods of treatment. Results:After two periods of treatment ,the subjective symptoms 、KPS 、weight 、the tumor marks(CEA+CA125) 、 immune parameters were significantly improved in the treated group ,better than in the control one.But there was no difference between two groups on the toxicity occurent rate and toxic degree were slighter in the treated group than in the control one.Conclusion: “Jian pi bu shen fang”combined with chemotherapy(DP regimen)has better curative effect on treating postoperative non-small cell lung cancer. Key words Jian pi bu shen fang; NSCLC; DP regimen; clinical study 目 录 引 言 1 临床研究 3 1 研究目的 3 2 病例选择 3 2.1 病例来源 3 2.2 纳入标准 3 2.3 排除标准 3 3 研究方法 3 3.1 治疗方法 4 3.2 治疗期间合并用药规定 4 3.3 统计分析方法 4 4 观察指标 4 5 疗效评定 4 5

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