辨病辨证结合治银屑病关节炎疗效分析.pdfVIP

Curative Effect Analysis of Psoriatic Arthritis Based on Combination of Disease and Syndrome Differentiation Speciality: TCM Internal Medicine of Rheumatism Author: Wang Haiyue Tutor: Prof. Song Shaoliang Abstract Objective: To evaluate curative effect of prescription based on combination of disease and syndrome differentiation, symptoms, signs and curative effects were compared between patients with psoriatic arthritis (PsA) in the two groups. Methods: Indexes of American College of Rheumatology (ACR) were choosed to evaluate arthritic effect, while Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) to evaluate psoriatic rash. After three months, decreases in TCM quantitative scores, ACR indexes, PASI and DLQI were analyzed in 40 PsA patients, who were equally assigned to experimental group with TCM prescription and control group with methotrexate. The number of responders to 20% improvement of ACR indexes (ACR20) and 50% improvement of PASI (PASI50) was compared in the two groups. Results: There were statistical differences between the two groups on proportion of patients who get a reductive TCM quantitative score on scale (P ＜0.05), and significant statistical differences on proportion of patients who get a score on thirst (P ＜0.01). There were statistical differences on scores on the patients pain on the visual analogue scale (VAS) and the Health Assessment Questionnaire (HAQ) (P ＜0.05). Conclusions: Combination of disease and syndrome differentiation is a correct method of PsA, whose prescription has a good effect on psoriatic arthritis and rash. Key Words