ISIS-4研究PPT课件.pptVIP

ISIS-4: Fourth International Study of Infarct Survival  Purpose To assess the separate and combined effects on all-cause mortality of adding early captopril, mononitrate and magnesium sulphate to conventional treatment of patients with definite or suspected acute MI Reference Fourth International Study of Infarct Survival Collaborative Group. ISIS-4: A randomized factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. Lancet 1995; 345: 669–85.  ISIS-4: Fourth International S