PICC中长期静脉治疗(国际)摘要.ppt

* * * * * * Catheter fibrin or thrombus may serve as a nidus for microbial colonization of intravascular devices and catheter thrombosis appears to be one of the most important factors associated with infection of long term catheters immediately following catheter insertion the catheter surface is coated with plasma and proteins ( fibrin, fibronectin) this is referred to as the host biofilm some microorganisms have high adherence to this host biofilm and produce a biofilm of their own to further enhance their adherence (extracellular slime) this extracellular slime permits the exchange of nut