SUV semiquantification in PETCT study.pptVIP

SUV semiquantification in PET/CT study By Men chao yang MD. SUV(標準攝取值)之重要性 可定義與比較不同時間點之增加或減少 以ROI之SUV判定惡性之高或低.效果類似 以Tl-201 or Ga-67 secondary or delayed imaging, the more SUV ratio in delayed time, the more malignancy could be reasonably suspected.目前中國大陸大部份醫院以50-90mins postinjection scan 為主. 原因: Benign lesion peak is 30 mins but malignant lesion peak is delayed to 60 mins. so, 90 mins imaging increased in L/N ratio, and could DDx benign or malignant, increased in accuracy.each bed collection time is 1.5 to 3 mins. SUV, location and configuration of uptake increased in accuracy of diagnosis. Delayed scan 2-3 hrs after this. But both acquisition data should be the same.(臺灣以40-60mins為主)? 2D 3D collection or scan: Pb or Tungstan as collimation or septa during a coincidence event detected by a direct plane or cross plane is 2D. Due to this reason, any length across two detector rings would be stopped by septa angle of collimation. 3 D get rid of collimation. And has more counts than 2D in the same time period. 3 D2D data and more ring more sensitivity. So it needs more correction method . Also decreased scatter effect by get rid of septa. 2D analysis of siemens PET 3D different SUV values automatic showed in one click of mouse: Imaging reconstruction FBP or OSEM Using 2D or 3D acquisitions is still under debate. Brain imaing use 3D for small activity concentrations outside the true FOV, could increased sensitivity. whole body imaging usually done in 2D mode. True FOV in 3D is larger than 2D! but hard to reconstruct. High sensitivity. Definition and formula: Normalized for body wt/surface area and injected dose. If really uniformly distributed over entire body, than SUV=1 Formula: ROI activity(mCi/mL)*body wt(g)/injected dose(mCi)= mL/g dependent to Lean body mass or body surface area can be substituted for body weight. More accurate for obese patient. PET/CT SUV is a quantitative value f