2008+药物性肝损伤的早期诊断和治疗实用指南分析报告.pdf

Online Submissions: World J Gastroenterol 2008 November 28; 14(44): 6774-6785 wjg@ World Journal of Gastroenterology ISSN 1007-9327 doi:10.3748/wjg.14.6774 © 2008 The WJG Press. All rights reserved. REVIEW Practical guidelines for diagnosis and early management of drug-induced liver injury Kazuto Tajiri, Yukihiro Shimizu Kazuto Tajiri, Department of Gastroenterology and of Hepatology, Postgraduate Institute of Medical Education and Hematology, Graduate School of Medical and Pharmaceutical Research, Chandigarh 160012, India Sciences, University of Toyama, Sugitani 2630, Toyama, Japan Yukihiro Shimizu, Center for Gastroenterology and Hepatology, Tajiri K, Shimizu Y. Practical guidelines for diagnosis and Kyoto Katsura Hospital, 17 Yamada-Hirao, Nishikyo, Kyoto early management of drug-induced liver injury. World J 615-8256, Japan Gastroenterol 2008; 14(44): 6774-6785 Available from: URL: Author contributions: Tajiri K reviewed and summarized /1007-9327/14/6774.asp DOI: http:// previous reports on drug-induced liver injury; Shimizu Y /10.3748/wjg.14.6774 organized the design of the manuscript; Both authors contributed equally to writing the manuscript. Correspondence to: Yukihiro Shimizu, MD, PhD, Center for Gastroenterology and Hepatology, Kyoto Katsura Hospital,17 Yamada-Hirao, Nishikyo, Kyoto 615-8256, INTRODUCTION Japan. yukihiro@ Telephone: +81-75-391-5811 Fax: +81-75-381-0090 Drug-induced liver injury (DILI) is a common liver Received: October