1红外线治疗--SCI文章.ppt

Effect of Far Infrared Therapy on Arteriovenous Fistula Maturation: An Open-Label Randomized Controlled Trial Contact Us Lorem ipsum dolor, 03663, State, Country P. 123 456 7890 / email@ START HERE 红外线治疗对动静脉內瘘成熟的作用：一个非盲随机对照研究 Background 1 of 6 Based on recommendations in the NKF-KDOQI guidelines, arteriovenous fistulas (AVFs) should be the first choice among different types of vascular access on account of their lower complications and higher long-term patency.However, vascular access complications still contribute to about 17%-25% of HD patient hospitalizations in the United States. These complications usually result from AVF malfunction caused by mechanical, medical, and genetic factors that have been reported to have significant roles in determining the patency ofAVFs.In patients with advanced stages of chronic kidney disease (CKD), an important cause of malfunction of newly created AVFs is failure to mature. KDOQI指南推荐，动静脉內瘘因其并发症发生率低而长期开放率高，是多种血管通道的首选方式。但是，在美国，17%-25%血透病人因血管通路的并发症而住院。 这些并发症通常是由于內瘘失功而引起的。 对于CKD晚期病人，新建內瘘失功的一个重要原因就是內瘘不能发展成熟。 Background 1 of 6 ......far infrared therapy, a convenient and noninvasive technology, can improve access flow and patency with reduction of AVF malfunction in HD patients. As described in recent studies, far infrared therapy might enhance endothelial function and skin blood flow and decrease the frequency of some cardiovascular diseases. Moreover, we also demonstrated that far infrared therapy may stimulate the expression of heme oxygenase 1 (HO-1).......thermal therapy may stimulate the expression of several enzymes targeting different pathogenetic mechanisms of AVF malfunction. 前期的研究表明，无创性的红外线治疗，可以改善血流和內瘘的开放程度，从而减少内瘘失功率。另外也有研究表明，红外线治疗可能增强内皮细胞的功能和皮肤的血流，减少心血管疾病；同时也能刺激血红素氧化酶1（HO-1）的表达。 红外线治疗作为热疗的其中一种方式，可能通过刺激多种酶的表达，针对AVF失功不同方面的病理机制起作用。 Hypothesis 1 of 6 假设：红外线治疗治疗可以促进动静脉内瘘的成熟。 We hypothesized that far infrared therapy may improve AVF maturation. Investigation This study aimed to investigate prospectively the effect of far