体外循环中不同预充方式对小儿先心术后输血量及早期降钙素原水平的影响.docVIP

体外循环中不同预充方式对小儿先心术后输血量及早期降钙素原水平的影响 　　[摘要] 目的 比较观察在小儿心脏手术体外循环中使用自体血预充技术与传统预充方式对术后输血量及早期降钙素原水平的影响。 方法 选择2012年6月～2014年6月在江门??五邑中医院心脏外科拟行先天性心脏病外科手术的60例患儿作为研究对象，按随机原则分为观察组（自体血预充组）和对照组（传统预充组），每组各30例。两组患儿均采用6%羟乙基淀粉130/0.4预先填充各自管路，对照组转机前不放血，观察组体外循环启动前先采用自体血预充技术置换出大部分最初预充液。治疗期间记录两组患儿术后异体血输入量及血流动力学变化，分别在体外循环前（T0）、术毕回ICU后（T1）、术后第1天（T2）、术后第2天（T3）、术后第3天（T4）5个时间点抽血检验血细胞比容和降钙素原水平。所得数据均采用统计学软件SPSS 20.0进行处理分析。 结果 T0、T1、T2时，自体血预充组患儿的血细胞比容水平均明显高于传统预充组，差异均有统计学意义（P 0.05）。 结论 自体血预充技术可安全使用于小儿体外循环，且能明显减少术后异体血使用量，值得临床上进一步优化并推广应用。 中国论文网 /6/view-7218241.htm 　　[关键词] 自体血预充；体外循环；输血量；血细胞比容；降钙素原 　　[中图分类号] R654.1 [文献标识码] A [文章编号] 1673-7210（2016）01（a）-0083-04 　　Influence of different priming methods on the rate of blood tansfusion and early serum procalcitonin level in children after congenital heart surgery during cardiopulmonary bypass 　　CHEN Zhenhua LUO Xiaozhen 　　Department of Anesthesiology， Wuyi Traditional Chinese Medicine Hospital of Jiangmen City， Guangdong Province， Jiangmen 529000， China 　　[Abstract] Objective To compare the influence of autologous priming and traditional priming methods during cardiopulmonary bypass in child cardiac surgery on the rate of blood transfusion after operation and early serum procalcitonin level. Methods 60 patients who intended to do congenital heart disease surgery in the Department of Cardiac Surgery in Wuyi Traditional Chinese Medicine Hospital of Jiangmen City from June 2012 to June 2014 were selected as research objects， they were divided into observation group （autologous priming group） and control group （traditional priming group） according to randomized principle， 30 cases in each groups. 6% hydroxyethylstarch 130/0.4 was used to prefill pipeline. Control group was not bleed before anesthesia. Autologous priming was used to replace most first priming solution before cardiopulmonary bypass in observation group. Homologous blood transfusion volume and hemodynamic changes after operation of patients in two groups during treatment were record. Leve