提纯麻醉椒内酯具有神经保护特性.docVIP

提纯的麻醉椒内酯具有神经保护特性 卡瓦或卡瓦卡瓦（卡瓦胡椒）是用于生产具有镇定作用饮料的植物。其中麻醉椒内酯是卡瓦饮料的主要成分。有许多临床试验证实卡瓦产物可作为抗焦虑的药物使用，并且已有系统评价支持了这一观点，即卡瓦基本上可用于治疗焦虑症。但同时也有研究提出了其对肝脏会产生不良反应。卡瓦提取物或麻醉椒内酯的研究都集中在其抗焦虑和睡眠诱导能力的机制中，这是归因于它对GABA受体的调制。 中国台湾朝阳科技大学Meng-Jen Lee教授表示，最近的研究已揭示出提纯的麻醉椒内酯会产生的神经保护特性，并与GABA能神经效应没有直接关系。这表示卡瓦胡椒可以用于许多退行性疾病或神经系统条件下的治疗。相关内容发表在2015年6月第6期《中国神经再生研究（英文版）》杂志上。 Article: Neuroprotective properties of kavalactones by Yew-Min Tzeng, Meng-Jen Lee, (Department of Applied Biochemistry, Chaoyang University of Technology, 168 Gifeng East Road, Wufeng, Taichung 41349, Taiwan, China) Tzeng YM, Lee MJ (2015) Neuroprotective properties of kavalactones. Neural Regen Res 10(6):875-877. 欲获更多资讯：请与《》联络；联络电话：，或用电子邮件联络：eic@。/ Neuroprotective properties of kavalactones Kava or kava-kava (Piper methysticum) is a plant used for the production of a ritual drink with transquilizing properties. The kavalactones are the main compounds of the kava drinks. There are many clinical trial for kava product for the use for anti-anxiety, and a systematic review supports the use of kava in treatment of generalized anxiety. Adverse effect on liver was reported, and kava is regulated in a number of countries. The study of kava extract or kavalactones have been focused on the mechanism for its anti-anxiety, sleep inducing ability, which has been attributed to its modulation to the GABA receptor. Prof. Meng-Jen Lee (Chaoyang University of Technology, Taiwan, China) showed that recent studies on the mechanisms of action for isolated kavalactones have revealed other neuroprotective activities not directly related to its GABAergic effects. This suggests that the use of kava might also benefit many degenerative disease or condition of the nervous system. The relevant study has been published in the Neural Regeneration Research (Vol. 10, No. 6, 2015). Article: Neuroprotective properties of kavalactones by Yew-Min Tzeng, Meng-Jen Lee, (Department of Applied Biochemistry, Chaoyang University of Technology, 168 Gifeng East Road, Wufeng, Ta