封闭-ohlearning.ppt

Typical Isolator典型隔离装置 Source: GSK – reproduced with permission来源：GSK——经许可转载 Half Suit Isolator半套隔离装置 Source: GSK – reproduced with permission来源：GSK——经许可转载 Simple Example of Containment简单封闭范例 Source: GSK – reproduced with permission来源：GSK——经许可转载 Bag Filling Unit装袋设备 Source: GSK – reproduced with permission来源：GSK——经许可转载 Decanting Product into Plastic Liner Inside Drum将产品倒入桶中的塑料管衬 Source: GSK – reproduced with permission来源：GSK——经许可转载 Modified Extraction Hood改进的抽气罩 Source: GSK – reproduced with permission来源：GSK——经许可转载 High Level Containment Systems (cont)高级封闭系统（续） The level of containment achieved at this level is refined by using increasingly more complex forms of engineering高级封闭采用更复杂的工程形式实现。 Example例如 three different levels of containment used for shutting off the supply of powder when filling containers by gravity feed当利用重力自流进料的方式充注容器时，可采用了三种不同级别的封闭来避免粉尘的产生。 Stage 1步骤1 At the first stage a simple butterfly valve cuts off the gravity feed of powder from above第一步，一个简单的蝶形阀切断了从上部供应的粉末的自流输送 This prevents mass leakage of the material but leaves the container open some residue at the mouth of the butterfly valve这将防止大量原料的泄漏，但会使容器打开，在蝶形阀入口处留下一些残留物 Stage 2步骤2 At the second stage the container is physically connected to the dispensing unit and a split butterfly valve is fitted第二步，容器实际上和分发设备相连，并装有分体蝶形阀 The split butterfly valve seals both the supply and the container but leaves the possibility that small quantities of material are left at the point where the two valves meet分体蝶形阀密封了供应装置和容器，但是有可能在两个阀门结合处留有少量的物质 Stage 3步骤3 At the third stage a split butterfly valve is used but a compressed air supply is also used to blow residue off the valve before it is closed第三步，使用了分体蝶形阀，同时也使用了压缩空气供给设备，在阀门关闭前吹走上面的残渣 Source: Adrian Hirst – reproduced with permission来源： Adrian Hirst ——经许可转载 Stage 1 步骤1 Stage 2步骤2 Stage 3步骤3 Types of Equipment used in High Level Containment高级封闭中使用的设备类型 Isolators 隔离装置 Clean room technology 无尘室技术 In process cleaning – washing