慢性肝病和肝纤维化__尤红.ppt

慢性肝病和肝纤维化 Hepatic Fibrosis is the Liver’s Wound Healing Response to Many Chronic Injuries Natural History of Chronic Liver Disease Progression of Liver Fibrosis in HCV Hepatic Stellate cells - Perisinusoidal cells of Normal Liver Cirrhosis is Reversible! Evidence in: HBV HCV Secondary biliary cirrhosis AIH PBC Wilson’s disease Thalassemia after bone marrow xplant Animal models 2007年AASLD 慢性乙型肝炎临床指南 Lok A S F, McMahon B J. Hepatology 2007; 45(2): 507-539 指南共包括41条推荐意见 防止HBV感染 慢性感染人群疾病的控制 慢性HBV感染患者评价 慢性乙肝的治疗 慢乙肝患者的临床咨询 HBsAg阳性人群应该： 使性伴侣接种乙肝疫苗、如果性伴侣未进行免疫接种或者未产生自然免疫，建议在性交时使用安全套 不共用牙刷和剃须刀 包