RNA干涉课件精要.ppt

* * * * * * * * * RNase H是一种核糖核酸内切酶，特异性水解DNA：RNA杂交链上RNA链的磷酸二酯键，产生5核苷酸，该酶对单链的核酸、双链DNA或双链RNA没有作用。 * * * 在这种情况下，RNA干扰并非抑制某一特定的基因，而是触发了眼部正常的免疫响应，才使得血管生长减少。 * * * RNA polymerase II (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA In the process of transcription (by any polymerase) there are three main stages: Initiation; the construction of the RNA polymerase complex on the genes promoter with the help of transcription factors. Elongation; the actual transcription of the majori