血吸虫候选疫苗的研究现状与展望解决方案.docVIP

血吸虫候选疫苗的研究现状与展望 摘要：血吸虫病是一种严重危害人民身体健康的人畜共患寄生虫病，发展疫苗是预防和控制日本血吸虫病的重要措施之一。血吸虫病疫苗的研制工作已纳入WHO和我国主要疾病防治规划并取得了显著进展。近年来开展的血吸虫免疫机制和血吸虫基因组研究对血吸虫疫苗的研制起了积极的推动作用，目前各国研究的焦点主要集中在疫苗候选分子方面。对近年来有前途的几种血吸虫疫苗的研究进展予以综述。 关键词：日本血吸虫；蛋白疫苗；DNA 疫苗；树突状细胞疫苗；综述 Current Status and Prospects on Candidate Vaccines against Schistosoma japonicum Abstract: Schistosomiasis, a parasitic diseases can both infect human and livestocks, made serious harmful to people’s health in recently years.An important method of schistosomiasis control is the creation of vaccines. Great progress has been made on vaccine research for schisto