+DNA的复制分析.pptVIP

* * * * Replication termini in E. coli are located beyond the point at which the replication forks actually meet. * * U * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 起始因子蛋白的三个功能: (1) binds to replicator, (2) distorts/unwinds a region of DNA, (3) interacts with and recruits additional replication factors DnaA in E. coli (all 3 functions), origin recognition complex (ORC) in eukaryotes (functions 1 3) 蛋白质和蛋白质及蛋白和DNA的相互作用指导了起始过程 Binding and unwinding DnaA recruits(募集)the DNA helicase DnaB and the helicase l