ControlofProkaryoticGeneExpression分析.pptVIP

第十一章 原核基因表达的调控Chapter 11 The Control of Prokaryotic Gene Expression 本章的主要内容: 1. 原核生物基因表达调控的要点; 2. 操纵子学说的主要内容; 3. 乳糖操纵子的发现及其意义; 4. 乳糖操纵子的主要调控方式; 5. 色氨酸操纵子主要调控方式； 6. 反义RNA技术的基本原理。 The basic concept of genetic regulation in bacteria is that the expression of a gene may be controlled by a regulator that interacts with a specific sequence or structure in DNA or mRNA at some stage prior to the synthesis of protein. Transcription often is controlled at the stage of initiation, not usually at elongation, but may be controlled at termination. Translation may be regulated, usually at the st