Chemophotodynamictherapy课程.pptx

细胞增殖周期;抗恶性肿瘤化疗药物;干扰核酸合成的药物; 药物;药物;破坏DNA结构与功能药 —金属化合物;破坏DNA结构与功能药 —喜树碱类;药物;抑制蛋白质合成药;干扰体内激素平衡药;氟脲嘧啶;临床用药原则;肿瘤化疗参考表;次敏感肿瘤;低敏感肿瘤;Enhanced therapeutic efficacy: additive or synergistic effects Reduced side effects: reduce the effective doses Retarded drug-resistance problem: different mechnisms;Sequential administration of a photosensitizer and an anticancer drug The use of their covalent and noncovalent conjugates Coencapsulation of these agents in a polymeric nanocarrier;Sequential administration (1);Sequential administration (2);Tumor volume;Sequential administration (3);HPPH-PDT Enhances Vascul